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Author Correction: Neoadjuvant study of niraparib in patients with HER2-negative, BRCA -mutated, resectable breast cancer

BREAST(2022)

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Abstract
This single-arm pilot study (NCT03329937) evaluated neoadjuvant niraparib antitumor activity and safety in patients with localized HER2-negative, BRCA -mutated breast cancer. Twenty-one patients received niraparib 200 mg once daily in 28-day cycles. After 2 cycles, tumor response (≥30% reduction from baseline) by MRI was 90.5% and 40.0% (6 of 15) of patients who received only niraparib (2–6 cycles) had pathological complete response; no new safety signals were identified. High niraparib intratumoral concentration was observed.
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Key words
Breast cancer,Cancer,Cancer therapy,Targeted therapies,Life Sciences,general
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