P25.03 Novel Diagnosis Technique for Identification of Asbestos Fibres in Mesothelioma Samples using LA-ICP-MS Imaging

Malignant mesothelioma (MM) is an aggressive cancer of the mesothelium associated with occupational and environmental exposure to asbestos and other mineral fibres (MF). There is an urgent need to develop methods to clearly identify and quantify the MF within biological samples. The aim of the current project is to identify MF based on their metal content within MM in vitro models as well as patient samples using laser ablation-inductively coupled plasma-mass spectrometry imaging (LA-ICP-MSI).