Comprehensive review of genotoxicity data for diclofenac

Andreas Hartmann, Linda Erkman, Nihal Maremanda,Azeddine Elhajouji,Hans-Joerg Martus

Mutation Research/Genetic Toxicology and Environmental Mutagenesis（2021）

引用 5|浏览7

暂无评分

摘要

•Comprehensive set of in vitro and in vivo genotoxicity studies for diclofenac.•Studies conducted for marketing approval of diclofenac presented for the first time.•Bacterial and mammalian in vitro assays demonstrated no genotoxicity.•Substantiated by in vivo assays with somatic/germ cells and dominant lethal test.

查看译文

关键词

Diclofenac,Genotoxicity,Mutagenicity,Chromosome aberrations,In vitro test,In vivo test

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要