FP09.01 Economic Impact of Screening Selection with the PLCOm2012 Risk Model Versus USPSTF-Guidelines in the International Lung Screening Trial (ILST)

Screening protocols that use model-estimated risk for selection are thought to improve the efficiency of lung cancer screening by reducing the number needed to screen and detecting more lung cancers. Since risk selection enriches screening populations with greater age and tobacco smoke exposure, some hypothesize that screening with model-based risk selection would be less cost-effective than more broadly defined selection criteria such as those defined by the USPSTF. The objective of this study is to examine the costs and cost-effectiveness of selection with the PLCOm2012 risk model versus USPSTF-based selection in the International Lung Screening Trial (ILST).