MA01.09 Efficacy and Safety of Glembatumumab Vedotin in Patients With Advanced or Metastatic Squamous Cell Carcinoma of the Lung (PrECOG 0504)
Journal of Thoracic Oncology(2021)
Abstract
Glycoprotein nmb (gp-NMB) is a transmembrane protein expressed in a variety of cancers; it has been linked with poor prognosis. The majority of patients with squamous lung cancer have high cellular expression of gp-NMB. Glembatumumab vedotin is an antibody-drug conjugate targeting gp-NMB.
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Key words
glembatumumab vedotin,metastatic squamous cell carcinoma,squamous cell carcinoma,lung
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