P0125 / #900: NUTRITIONAL SUPPORT IN A PEDIATRIC INTENSIVE CARE UNIT

Aims & Objectives: To evaluate the prescription of nutrients (calories and protein) of patients admitted to a Pediatric Intensive Care Unit (PICU) and their relationship with outcomes. Methods: A retrospective observational cohort study conducted in a PICU for a period of two years. Patients who were hospitalized for at least three days and received enteral nutrition (EN) via tube and / or parenteral nutrition (PN) were included. Demographic data, severity score (PIM 2), daily prescription of diet volume, energy and protein value, length of stay, need for mechanical ventilation, organ dysfunction and mortality were collected. Basal energy expenditure (BEE), according to Schofield (1985), was considered as caloric goal. The protein target was considered to be 70% of the minimum recommended age value by ASPEN. Results: We included 352 patients. Energy underprescription was observed in 201 patients (42.9%). Insufficient energy supply was significantly associated with multiple organ dysfunction (p = 0.015) and gastrointestinal (p = 0.011), cardiac (p = 0.003), renal (p0.046), and hepatic (p = 0.005) disorders. There was also an association with sepsis (p = 0.008), septic shock (p = 0.007) and mortality (p = 0.120). Only 132 patients (37.5%) reached the protein prescription goal. When analyzing the outcomes, among patients who received and did not receive the protein goal, a significant association was observed regarding sepsis (p0.044), septic shock (p0.025) and mortality (p0.034). Conclusions: Nutrient prescribing in the study population is below recommendations and is associated with negative outcomes in this group of patients.