Association of interleukin-17 A gene variants and susceptibility to H. pylori related gastric diseases

Mehdi Kalani, Seyed-Amin Kouhpayeh,Seyedeh Azra Shamsdin,Javad Jamshidi,Maral Choopanizadeh, Gholamhossein Keighobadi,Ali Moravej

Meta Gene(2021)

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摘要
•A allele (rs3819024) in IL-17 gene was more frequent in the patients with chronic active gastritis than the controls.•Homozygous rs3819024GG in IL-17 gene was significantly more frequent in the controls than the patients.•AA haplotype (rs4711998A/rs3819024A) in IL-17 gene was more frequent in the patients than the controls.•A allele (rs3819024) and AA haplotype (rs4711998/rs3819024) in IL-17 gene are associated with gastric inflammatory diseases.
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关键词
IL-17A,Polymorphism,Helicobacter,Gastritis,Peptic ulcer
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