Analysis of tissue displacement induced by high-intensity focused ultrasound exposure for coagulation monitoring

Decorrelation between two ultrasound images has been investigated for real-time monitoring of lesion formation caused by high-intensity focused ultrasound (HIFU) exposure. However, the origin of the decorrelation remains unclear. In this study, the distributions of tissue displacement were obtained from numerical simulation and experimental data, and the latter was compared to the decorrelation map. The results show the possibility that decorrelation of ultrasonic signals can be explained by thermal expansion and apparent displacement caused by the temperature dependence of the speed of sound.