Carbon-ion radiotherapy boost with standard dose proton radiation for incomplete-resected high-grade glioma: a phase 1 study.

Xianxin Qiu,Jing Gao,Jing Yang,Jiyi Hu,Weixu Hu,Qingting Huang,Lin Kong,Jiade J Lu

Annals of translational medicine（2022）

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摘要

Particle beam radiotherapy consisting of a CIRT boost of 15 Gy RBE (in 3 fractions) following standard dose PRT (60 Gy RBE in 30 fractions), and used in conjunction with TMZ, is safe and potentially effective for patients with HGG.

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关键词

Glioblastoma (GBM),anaplastic astrocytoma (AA),carbon-ion radiotherapy (CIRT),proton radiotherapy (PRT),temozolomide (TMZ)

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