Phase Ii Trial Of Opaganib In Patients With Metastatic Castration-Resistant Prostate Cancer Progressing On Abiraterone Or Enzalutamide (Nct04207255).

Omer Kucuk,Charles Smith,Terry Plasse,Besim Ogretmen,Shikhar Mehrotra,Theodore Stewart Gourdin,Mehmet Asim Bilen,Bradley Curtis Carthon,Bassel Nazha,Jamie Goldman,Michael B. Lilly

JOURNAL OF CLINICAL ONCOLOGY（2021）

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Abstract

TPS191Background: Opaganib (Yeliva, ABC294640) is a first-in-class, sphingosine kinase-2 (SK2) selective inhibitor, with anticancer, anti-inflammatory and anti-viral activities. SK2, a lipid kinase...

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Key words

opaganib,prostate,abiraterone,castration-resistant

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