Hypothalamic-pituitary-adrenal axis regulation and organization in urban and rural song sparrows

Samuel J Lane,Michael G Emmerson,Isaac J VanDiest,Catherine Hucul,Michelle L Beck,Scott Davies,Elizabeth R Gilbert,Kendra B Sewall

General and Comparative Endocrinology（2021）

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摘要

•Inhabiting novel habitats may require rapid recovery from frequent disturbance.•Efficient termination of the GC stress response could aid urban adapters.•Urban & rural males do not differ in response to a dexamethasone challenge.•Urban males have lower hippocampal GR & 11β-HSD2.

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关键词

Urbanization,Glucocorticoid receptor,Mineralocorticoid receptor,11β-HSD2,Glucocorticoids,Dexamethasone

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