Mp03-10 open adrenalectomy versus laparoscopic adrenalectomy for adrenocortical carcinoma: a retrospective comparative study on short-term oncological prognosis

You have accessJournal of UrologyAdrenal1 Apr 2018MP03-10 OPEN ADRENALECTOMY VERSUS LAPAROSCOPIC ADRENALECTOMY FOR ADRENOCORTICAL CARCINOMA: A RETROSPECTIVE COMPARATIVE STUDY ON SHORT-TERM ONCOLOGICAL PROGNOSIS Guo-yang Zheng, Han-zhong Li, and Xue-bin Zhang Guo-yang ZhengGuo-yang Zheng More articles by this author , Han-zhong LiHan-zhong Li More articles by this author , and Xue-bin ZhangXue-bin Zhang More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.3053AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Open approach remains the gold standard of surgical therapy for adrenocortical carcinoma, while the efficacy of laparoscopic approach is controversial. We aim to explore short-term oncological prognosis of adrenocortical carcinoma by comparing clinical data between open with laparoscopic adrenalectomy. METHODS We retrospectively analyzed baseline characteristics, perioperative data and postoperative prognosis of 42 patients with adrenocortical carcinoma receiving open adrenalectomy (n=22) and laparoscopic adrenalectomy (n=20) as primary treatment. RESULTS Open adrenalectomy group had larger maximum diameter of tumor, and less benefits in perioperative data than laparoscopic adrenalectomy. Mean disease-free survival of open adrenalectomy was 44.8±35.1 months, longer than 17.5±10.4 months of laparoscopic adrenalectomy. Rate of 2-year disease-free survival in open adrenalectomy group was higher than laparoscopic adrenalectomy group (61.1% vs 21.4%), but rate of 1-year and 3-year disease-free survival showed no significant difference. All patients with laparoscopic adrenalectomy were found local lesions at the first time of recurrence, while 5 of 13 patients with open adrenalectomy did not appear local recurrence. CONCLUSIONS Open adrenalectomy for adrenocortical carcinoma is superior to laparoscopic approach in disease-free survival and rate of 2-year disease-free survival. Patients after laparoscopic adrenalectomy are more likely to appear local recurrence at the first time of relapse. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e25-e26 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Guo-yang Zheng More articles by this author Han-zhong Li More articles by this author Xue-bin Zhang More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...