Urine metabolomic biomarkers for prediction of isolated fetal congenital heart defect.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians（2022）
摘要
We report a novel, noninvasive approach, based on the analysis of maternal urine for isolated CHD detection. Further, the dysregulation of lipid- and folate metabolism appears to support prior data on the mechanism of CHD.
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关键词
Metabolomics,congenital heart defect,mass spectrometry,metabolites,nuclear magnetic resonance
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