Pegylated liquisomes: A novel combined passive targeting nanoplatform of L-carnosine for breast cancer

Passent M.E. Gaafar,Noha S. El-Salamouni,Ragwa M. Farid,Heba A. Hazzah,Maged W. Helmy,Ossama Y. Abdallah

International Journal of Pharmaceutics（2021）

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摘要

•L-carnosine phospholipid complex is incorporated in PEGylated liquid crystalline nanoparticles.•PEGylated Liquisomes protected L-carnosine in-vivo, prolonged it’s release and enhanced its anti-cancer activity.•PEGylated Liquisomes offered precious anti-cancer activity with superior safety profile.

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关键词

L-carnosine,Liquisomes,Phytosomes,Anti-cancer,Cytotoxicity,Phospholipid complex

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