In Comparison To Pathological Q Waves, Selvester Score Is A Superior Diagnostic Indicator Of Increased Long-Term Mortality Risk In St Elevation Myocardial Infarction Patients Treated With Primary Coronary Intervention

DIAGNOSTICS(2021)

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摘要
The development of pathological Q waves has long been correlated with worsened outcome in patients with ST elevation myocardial infarction (STEMI). In this study, we investigated long-term mortality of STEMI patients treated by primary percutaneous coronary intervention (PPCI) and compared predictive values of Q waves and of Selvester score for infarct volume estimation. Data of 283 consecutive STEMI patients (103 females) treated by PPCI were analysed. The presence of pathological Q wave was evaluated in pre-discharge electrocardiograms (ECGs) recorded >= 72 h after the chest pain onset (72 h Q). The Selvester score was evaluated in acute ECGs (acute Selvester score) and in the pre-discharge ECGs (72 h Selvester score). The results were related to total mortality and to clinical and laboratory variables. A 72 h Q presence and 72 h Selvester score >= 6 was observed in 184 (65.02%) and 143 (50.53%) patients, respectively. During a follow-up of 5.69 +/- 0.66 years, 36 (12.7%) patients died. Multivariably, 72 h Selvester score >= 6 was a strong independent predictor of death, while a predictive value of the 72 h Q wave was absent. In high-risk subpopulations defined by clinical and laboratory variables, the differences in total mortality were highly significant (p < 0.01 for all subgroups) when stratified by 72 h Selvester score >= 6. On the contrary, the additional risk-prediction by 72 h Q presence was either absent or only borderline. In contemporarily treated STEMI patients, Selvester score is a strong independent predictor of long-term all-cause mortality. On the contrary, the prognostic value of Q-wave presence appears limited in contemporarily treated STEMI patients.
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关键词
primary percutaneous coronary intervention, Q wave, Selvester score, ST elevation myocardial infarction
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