Preliminary In Vitro Study Of Fluoride Release From Selected Ormocer Materials

The purpose of the in vitro study presented in this paper was to determine the long-term release of fluoride ions from selected ormocer materials (Admira (A), Admira Flow (AF), Admira Seal (AS)). The release of fluoride ions from these materials into a saline solution (0.9% NaCl) and deionized water was tested for 14 weeks. In a long-term study the measurements were taken after 1 and 3 h, then 1, 2, and 3 days and then at weekly intervals for 14 weeks. In a short-term study the measurements were made after 3, 24, 48, 72, 69, 168 h, i.e., within 7 days. All materials used in the test showed a constant level of fluoride release. The highest level of cumulative release of fluoride ions into deionized water was found in the AS material (23.95 +/- 4.30 mu g/mm(2)), slightly lower in the A material (23.26 +/- 4.16 mu g/mm(2)) and the lowest in the AF material (16.79 +/- 2.26 mu g/mm(2)). The highest level of cumulative release into saline solution was found in AF (8.08 +/- 1.30 mu g/mm(2)), slightly lower in AS (7.36 +/- 0.30 mu g/mm(2)) and the lowest in A (6.73 +/- 1.10 mu g /mm(2)). After 1 h of immersion of the samples in the saline solution, the highest level of fluoride was released by AF (0.57 +/- 0.06 mu g/mm(2)) followed by A (0.20 +/- 0.03 mu g/mm(2)) and AS (0.19 +/- 0.02 mu g/mm(2)). Moreover, in the 14-week study, the total amount of fluoride release into the saline, which imitates the environment of the oral cavity, was observed as the highest in the AF sample.