Ardisiatetrons A and B: tetronic acid derivatives and triterpenes from the leaves of Ardisia quinquegona and their biological activity

From the leaves of Ardisia quinquegona , two alkylated tetronic acid derivatives, named ardisiatetrons A and B ( 1 , 2 ), and four triterpenoids ( 3 – 6 ) were isolated together with one known compound ( 7 ) by a combination of various kinds of chromatography. The structure of new methyl migrated triterpene ( 3 ) was confirmed by X-ray crystallographic analysis. Compounds 2 , 3 , and 7 showed moderate anti- Leishmania activity and cytotoxicity towards A549 cells. Graphic abstract