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Evaluating Differences In Whole Blood, Serum, And Urine Screening Tests For Zika Virus, Puerto Rico, Usa, 2016

Asher Y Rosinger,Samantha M Olson,Sascha R Ellington,Janice Perez-Padilla,Regina M Simeone,Caitlin S Pedati,Betsy A Schroeder,Gilberto A Santiago,Freddy A Medina,Jorge L Muñoz-Jordán,Laura E Adams,Romeo R Galang,Miguel Valencia-Prado,Sonia Bakkour,Candimar Colón,Mary Goodwin,Dana Meaney-Delman,Jennifer S Read,Lyle R Petersen,Denise J Jamieson,Carmen C Deseda,Margaret A Honein,Brenda Rivera-García,Carrie K Shapiro-Mendoza

EMERGING INFECTIOUS DISEASES（2021）

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Abstract
We evaluated nucleic acid amplification testing (NAAT) for Zika virus on whole-blood specimens compared with NAAT on serum and urine specimens among asymptomatic pregnant women during the 2015-2016 Puerto Rico Zika outbreak. Using NAAT, more infections were detected in serum and urine than in whole blood specimens.
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Key words
NAAT,PCR,Puerto Rico,United States,Zika virus,mosquito-borne diseases,mosquitos,nucleic acid amplification testing,outbreak,pregnancy,vector-borne diseases,viruses,whole blood,zoonoses
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