Combination of platelet rich plasma and stromal vascular fraction on the level of vascular endothelial growth factor in rat subjects experiencing deep dermal burn injury

•Stem cells can increase concentrations of growth factors.•Topical application and injection of stem cells significantly increased serum VEGF compared to control.•The VEGF concentration was significantly higher following injection of PRP and SVFs.•The injection route of stem cells is more effective at increasing VEGF levels compared to the topical application.