Marker for detecting drug for cardiovascular system

He Kunlun,Wu Jian,Jia Zhilong,Shi Jinlong,Zhao Xiaojing,Jia Qian, Cui Saijia, Yang Pengming,Ma Junfeng, Meng Fanfei

user-5dd52aee530c701191bf1b99(2019)

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摘要
The invention provides a marker for detecting a drug for the cardiovascular system, and provides the application of a reagent for detecting a gene related to drug metabolism of the drug for the cardiovascular system in preparing a product for researching the drug metabolism. The reagent can maximally detect 66 related genes. The reagent and the product containing the reagent are used for drug metabolism research, drug screening, drug efficacy evaluation or dose determination of the drug for the cardiovascular system, and molecular genetic testing of individual drug users and population censusaffecting drug efficacy polymorphism sites are carried out, in order to reduce the incidence of drug failure and adverse drug reactions; a probe set, a chip and a kit have the advantages of high efficiency, multiple detection sites, accuracy, simple operation, good specificity, high sensitivity, fastness, high practicability and low cost.
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关键词
Drug,Population,Drug metabolism,Reagent,Efficacy,Pharmacology,Medicine,Drug reaction,Molecular genetic testing
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