Uses of WNK kinase inhibitors in prevention and/or treatment of pulmonary hypertension

The present invention discloses uses of WNK kinase inhibitors in prevention and/or treatment of pulmonary hypertension, and particularly uses of WNK 463 in the prevention and / or treatment of pulmonary hypertension and complications thereof. Experiments by inventors of the present application find that the WNK kinase inhibitors (especially the WNK 463) show relatively good effects on protection of pulmonic circulation-right-heart pressure and function, right ventricular hypertrophy, etc. of monocrotaline (MCT)-induced pulmonary hypertension in rats, and have potential value of being developedinto drugs for the prevention and treatment of pulmonary hypertension and complications thereof.