Structure of Rad5 provides insights into its role in tolerance to replication stress

Miaomiao Shen,Nalini Dhingra,Quan Wang,Xiaoxin Gong,Xin Xu,Hengyao Niu,Xiaolan Zhao,Song Xiang

MOLECULAR & CELLULAR ONCOLOGY（2021）

引用 0|浏览8

暂无评分

摘要

The Rad5 family of proteins are critical genome maintenance factors, with helicase-like transcription factor (HLTF) and SNF2 histone linker PHD RING helicase (SHRPH) in humans implicated in several types of cancer. How their multiple activities coordinate has been unclear. Our recent study on Rad5 shed light on this question.

查看译文

关键词

Replication stress,Rad5,HLTF,HIRAN domain,protein structure

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要