INTRODUCTION TO SELECTING SUBSETS OF TRAITS FOR QUANTITATIVE TRAIT LOCI ANALYSIS

Conference on Applied Statistics in Agriculture(2010)

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摘要
Quantitative trait loci (QTL) mapping is a popular statistical method that is often used in agricultural applications to identify genomic regions associated with phenotypic traits of interest. In its most common form, a QTL analysis tests one phenotypic trait at a time using a variety of research hypotheses that depend on the application. When multiple traits are available, there are considerable benefits to analyzing subsets of biologically related traits in a multipletrait QTL mapping framework. Determining the most informative subset(s) of traits is the critical challenge that we address in this work. We present our approach, as well as simulations that demonstrate the performance. We also discuss an application of our approach as applied to an Arabidopsis thaliana data set.
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关键词
Family-based QTL mapping,Association mapping,Genetic architecture,Quantitative trait locus,Evolutionary biology,Biology
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