The peculiarities of the 4-carboxyphenylglyoxal and N-alkoxy-N’-arylureas interaction

It was found that 3-alkoxy-4,5-dihydroxyimidazolidin-2-ones are the only products of interaction of N -alkoxyureas with arylglyoxals which have strong electronegative substituent in the forth position of the aryl moiety. The possibility of obtaining such products as 3-alkoxy-1-aryl-5-(4-carboxyphenyl)-4,5-dihydroxyimidazolidin-2-ones, 3-alkoxy-1-alkyl-5-(4-carboxyphenyl)-4,5-dihydroxyimidazolidin-2-ones and 3-alkoxy-1-phenyl-4,5-dihydroxy-5-(4-nitrophenyl)-imidazolidin-2-ones has been verified in the experimental way. In most the cases 3-alkoxy-4,5-dihydroxyimidazolidin-2-ones were produced as a mixture of diastereomers