218 Role of frozen section in surgical staging of early – stage endometrial cancer: experience at hospital sotero del rio

Introduction EC has high incidence in Chile. Although most are diagnosed in early stages, some of them have ganglionar compromise at time of surgery. Taking in count morbidity associated with PPaLND, FS is determinant in staging. Objective to assess the agreement rate between contemporary and definitive biopsy and how it affects our clinical conduct. Methods retrospective analysis of clinical charts and pathology reports between 2005–2020 at Hospital Sotero del Rio. Statistical analysis based on software R version 3.6.1. Results 410 patients with early-stage EC and surgical treatment. Average age was 61 y-old (26–84), BMI 31 (17–56), 342 (83%) multiparous, most common comorbidities were hypertension and diabetes. We performed 282 (68.7%) FSs and 61 (22%) had a change in clinical conduct. Variables associated with it were histology, myometrial invasion and grade of differentiation(p=0.003 and p Conclusions FS is a determinant and feasible tool in clinical decisions respecting surgical staging.