Novel variants of the multicomponent reaction for the synthesis of 1,2,4-triazolo[1,5- а ]pyrimidines and pyrido[3,4- е ][1,2,4]triazolo[1,5- а ]pyrimidines

new multicomponent reaction for regioselective synthesis of substituted 1,2,4-triazolo[1,5- a ]pyrimidines using aminotriazoles, β-ketoglutaric acid dimethyl ester, and dimethylformamide dimethyl acetal was implemented. The selective reduction of 1,2,4-triazolo-[1,5- a ]pyrimidines to dihydro derivatives and the use of triazolo pyrimidines as starting compounds in multicomponent synthesis of dihydropyrido[3,4- е ][1,2,4]triazolo[1,5- a ]pyrimidinecarboxylates was demonstrated.