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Compositions and methods for cancer expressing pde3a or slfn12

Luc De Waal,Matthew Meyerson, Heidi Greulich,Monica Schenone,Alex Burgin, Ulricke Sack

user-5d8054e8530c708f9920ccce（2016）

Cited 4|Views1
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Abstract
The present invention features improved methods of identifying patients having cancer (e.g., melanoma, adenocarcinoma, lung, cervical, liver or breast cancer) using biomarkers (e.g., PDE3A, SLFN12) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., DNMDP, zardaverine, and anagrelide).
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Key words
Cancer,Breast cancer,Adenocarcinoma,Zardaverine,Anagrelide,Melanoma,Oncology,Biomarker (medicine),Drug,Medicine,Internal medicine
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