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Comparative Studies in the A30P and A53T Α-Synuclein C. Elegans Strains to Investigate the Molecular Origins of Parkinson's Disease

Michele Perni,Annemieke van der Goot,Ryan Limbocker,Tjakko J. van Ham,Francesco A. Aprile,Catherine K. Xu,Patrick Flagmeier,Karen Thijssen,Pietro Sormanni,Giuliana Fusco,Serene W. Chen,Pavan K. Challa,Julius B. Kirkegaard,Romain F. Laine,Kai Yu Ma,Martin B. D. Muller,Tessa Sinnige,Janet R. Kumita,Samuel I. A. Cohen,Renee Seinstra,Gabriele S. Kaminski Schierle,Clemens F. Kaminski,Denise Barbut,Alfonso De Simone,Tuomas P. J. Knowles,Michael Zasloff,Ellen A. A. Nollen,Michele Vendruscolo,Christopher M. Dobson

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY（2021）

Cited 14|Views35
Key words
elegans,Parkinson&apos,s disease,alpha-synuclein,drug discovery,protein aggregation,protein misfolding,neurodegenerative diseases,transgenic model
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