Treatment of Inflammatory Macular Hole: Case Series and Review of Literature

Purpose: To present the success rate of nonsurgical management of full-thickness inflammatory macular hole (IMH) Method: Retrospective case series of five patients with IMH. Result: Five eyes from five patients with IMH enrolled in the current case series. All five eyes had successful closure with corticosteroid in the form of topical, periocular, or intravitreal injections. Systemic immunomodulatory treatment was employed for two patients, in addition to local therapy. For local therapy, one patient received topical eye drops, subtenon injection of corticosteroid, and intravitreal injection of combination of corticosteroid and anti-VEGF was performed in two patients. The closed macular hole reopened in one patient after two years, which required pars plana vitrectomy and anatomical and visual success achieved. Conclusion: Inflammatory macular holes can be closed with non-surgical interventions, although reopening may occur which requires surgery.