Systematic Evaluation of Structure-Property Relationships and Pharmacokinetics in 6-(Hetero)aryl-substituted Matched Pair Analogs of Amiloride and 5-(N,n-hexamethylene)amiloride.
Bioorganic & Medicinal Chemistry（2021）
Key words
Amiloride,Urokinase,uPA,Cancer,Metastasis,Antimetastatic,Selective optimization of side activity,SOSA,Lead optimization
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