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NINJ1, rupturing swollen membranes for cataclysmic cell lysis

Yupeng Wang,Feng Shao

Molecular Cell（2021）

Cited 22|Views45
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Abstract
Using a forward-genetic screening of macrophages from randomly mutagenized mice, Kayagaki et al. (2021) identify NINJ1 that mediates plasma membrane rupture following various types of programmed cell death, an event previously thought to be passive.
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