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Pharmacogenetic algorithm for predicting daily dose of warfarin in Caucasian patients of Czech origin.

Aleš Tomek,Tereza Růžičková,Vojtěch Kaplan,Zuzana Lacinová,Simona Kumstýřová,Martin Šrámek,Anna Olšerová,Petr Janský,Tereza Kolářová,Jiří Neumann,Jaroslava Paulasová Schwabová,Václav Maťoška

Drug metabolism and personalized therapy（2020）

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Abstract
Our validated algorithm for warfarin daily dose prediction in our Czech cohort had higher precision than other currently published algorithms. Pharmacogenetics of warfarin has the potential in the clinical practice in specialized centers.
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Key words
CYP2C9,VKORC1,daily dose prediction algorithm,pharmacogenetics,warfarin
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