A polymeric micellar drug delivery system developed through a design of Experiment approach improves pancreatic tumor accumulation of calcipotriol and paclitaxel.
International journal of pharmaceutics(2021)
摘要
•The Design of Experiment approach enables faster drug delivery development with pre-defined performance parameters.•The Design of Experiment approach enables the definition of a design space for potential modifications of a delivery system.•Size-controlled micelles facilitate pancreatic tumor accumulation.
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