Association Of Co-Occurring Gene Alterations And Clinical Activity Of Rucaparib In Patients With Brca1 Or Brca2 Mutated (Brca Plus ) Metastatic Castration-Resistant Prostate Cancer (Mcrpc)

JOURNAL OF CLINICAL ONCOLOGY（2021）

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摘要

80Background: The poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib was granted accelerated approval by the US Food and Drug Administration for patients with BRCA+ mCRPC based on results from ...

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关键词

Rucaparib,Prostate cancer,Cancer research,Poly ADP ribose polymerase,Polymerase,Gene,Medicine,Castration resistant,Co occurring,Correlation and dependence

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