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Ploidy dynamics increase the risk of liver cancer initiation

Miryam Müller,Stephanie May,Thomas G. Bird

NATURE COMMUNICATIONS（2021）

Cited 11|Views4
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Abstract
Liver cancer typically arises after years of inflammatory insults to hepatocytes. These cells can change their ploidy state during health and disease. Whilst polyploidy may offer some protection, new research shows it may also promote the formation of liver tumours.
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Key words
Cancer genomics,Chromosome segregation,Science,Humanities and Social Sciences,multidisciplinary
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