Antiangiogenic effect of pinobanksin on human umbilical vein endothelial cells
Journal of Functional Foods(2021)
Abstract
•Pinobanksin inhibits the tube formation and migration of HUVECs.•Pinobanksin exhibits antiangiogenic effect by inducing endothelial cell apoptosis.•Pinobanksin suppresses new blood vessel growth of chick embryos.•Pinobanksin reduces the MEK/ERK activation and inhibits the cell adhesion molecules.
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Key words
Pinobanksin,Angiogenesis,Tube formation,Apoptosis,Human umbilical vein endothelial cells
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