Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients

Marina Farrel Côrtes,Bianca Leal de Almeida,Evelyn Patricia Sanchez Espinoza,Aléia Faustina Campos,Maria Luiza do Nascimento Moura,Matias C. Salomão,Icaro Boszczowski,Maristela Pinheiro Freire,Laina Bubach de Carvalho,Gláucia Paranhos-Baccalà,Silvia Figueiredo Costa,Thaís Guimarães

Diagnostic Microbiology and Infectious Disease（2021）

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摘要

Summary Ventilator associated pneumonia(VAP) is a severe complication that can lead to high mortality when not early identified or when therapy is delayed. The aim of this study was to evaluate procalcitonin(PCT) as a biomarker for VAP development. In total, 73 hospitalized patients with COVID-19 were analyzed. PCT levels greater than 0.975ng/ml were more related to VAP. No association was found for C-reactive protein (CRP). The results show that procalcitonin may be a pertinent biomarker for VAP diagnosis and can be a helpful tool for antibiotic withdrawal.

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