Potential anti-degenerative hypercholesterolemia in steeping tea with combination of leaves of pasote (dysphania ambrosioides l.), gedi (abelmoschus manihot l.), tapak dara (catharanthus roseus (l.) g. don)

Most of the Covid 19 victims were aged 50-70 years because at that age they had complications with degenerative diseases Curing degenerative diseases by utilizing traditional medicinal plants to increase resistance to Covid 2019 infection can heal itself into a new breakthrough It is hoped that the use of anti-degenerative supplements will also cure Covid 2019 Therefore, the development of this anti-degenerative supplement is very important as an immunomodulator, especially during the Covid 2019 outbreak Cholesterol in the blood is needed by the body, but consumption of foods that contain excessive saturated fat will increase cholesterol in the blood, causing hypercholesterolemia which is also the cause of plaque in the coronary heart This study aims to analyze the potential of several traditional medicinal plants by providing a combination of tea with Pasote (Dysphania ambrosioides), Gedi (Abelmoschus manihot) and Tapak dara (Catharanthus roseus) blood cholesterol levels on blood cholesterol levels of white rats (Rattus novergicus) The research method used is experimental The mice were induced with high fat for 2 weeks, then their blood cholesterol content was measured with Lipidpro, then treated with single steeping water and a combination of steeping water accompanied by negative and positive controls The results showed that cholesterol levels increased after administration of fat (initial cholesterol) and after treatment the cholesterol content decreased in all treatments The results of statistical tests indicate that the reduction in cholesterol levels in the treatment is significantly or significantly different at the 95% confidence level The highest reduction in cholesterol content was in the cholesterol levels of white rats that had been given a combination of steeping water of tapak dara, gedi and pasote leaf powder to 44 61% of the control, while the lowest reduction was the combination of Pasote and Tapak dara which was only 0 9% of the control The combination of Pasote, Gedi and Tapak Dara has the potential to be used as an anti-degenerative supplement, especially for reducing high cholesterol levels in patients with hypertension and hypercholesterolemia