Calcium Release from Different Toothpastes after the Incorporation of Tricalcium Phosphate and Amorphous Calcium Phosphate

This study aimed to investigate the free calcium released from different brands of toothpaste after incorporation with a beta-tricalcium phosphate (beta-TCP)/amorphous calcium phosphate (ACP) mixed powder and with beta-TCP powder alone. Four brands of toothpaste were used for the experiment: Nano-Bio Activation Toothpaste, Colgate Total Advanced Whitening Toothpaste, BORONIA Herbal Whitening, and BioMin F. The investigated beta-TCP and ACP powders were prepared by a two-step sintering method using raw coral material. Analytical results found that the mean calcium concentration of the beta-TCP/ACP (2:1) powder in deionized water was 3.4% when the pH was between 5 and 9. Moreover, statistical results revealed that the toothpaste containing beta-TCP powder had significantly higher calcium concentrations than the normal toothpaste. The toothpaste containing mixed beta-TCP/ACP powder had a higher calcium concentration than the toothpaste containing only beta-TCP powder. Twice as much free calcium could be released from beta-TCP/ACP toothpaste than from beta-TCP-only toothpaste. Thus, toothpaste containing beta-TCP/ACP mixed powder offers greater benefits to facilitate the remineralization of enamel than toothpaste containing only beta-TCP.