Resonant X-ray scattering of biological assemblies
MRS COMMUNICATIONS(2021)
摘要
Understanding the relationship between structure and function for biological assemblies can guide identification of new therapeutics, design of biomaterials, and development of biotechnological processes. Resonant X-ray scattering provides a chemically-specific approach to characterize complex biological structures based on anomalous or resonant scattering from a specific element or chemical moiety. Anomalous or resonant diffraction can provide structural details with high atomic resolution, while resonant X-ray scattering can provide structural details with lower resolution through tender or soft X-rays. Here, we review applications, challenges, and opportunities for resonant X-ray scattering in the field of structural biology. Graphic abstract
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关键词
Biological, Chemical composition, Heterogeneous, Microstructure, Protein, Tunable, X-ray diffraction (XRD)
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