809 Pregnancy latency among patients with preterm prelabor rupture of membranes attending inpatient centering groups

Outpatient CenteringPregnancy© groups have been shown to reduce rates of preterm birth, specifically in Black mothers, and increase breastfeeding rates, the inpatient use is limited and understudied. We sought to determine the impact of inpatient centering(IC) on latency among women admitted with preterm prelabor rupture of membranes(PPROM). Single institution, retrospective cohort study of women with PPROM participating in at least 1 IC group from 2019-2020 compared to historic controls from 2013-2019. Patients admitted after 33 weeks, age<18, higher order multiples or a latency <24hrs excluded. Primary outcome was pregnancy latency. Secondary outcomes included maternal morbidity, and 6wk post-partum(PP) breastmilk feeding. Analysis stratifying by race performed. Bivariate statistics compared IC cohort to controls. Regression models used to control for confounders. 11 women with PPROM participated in IC compared to 278 controls. IC women had higher rates of HTN, twins and anxiety(Table 1). IC women had longer median latency compared to controls(26 days[IQR:13, 29] vs8 days[3,14] p<0.01), as well as, increased rates of PP breastmilk feeding(91% vs 59% p<0.01)(Table 2). In regression models controlling for confounders, IC was associated with 10.2 day longer latency and 9.4-fold increased odds of PP breastmilk feeding(Table 2). When stratifying by race, Black women who participated in IC had longer median latency than Black controls (27.5vs20 days, p<0.01). This difference did not extend to White women(18vs10 days, p=0.13) or Latinx women(14.5vs7 days, p=0.88). In regression models, IC participation predicted 20.0 days longer latency for Black women, but was not a significant predictor of latency for White or Latinx women (Table 2). No significant differences in PP breastmilk feeding rates seen when stratified by race. This pilot Inpatient Centering study demonstrated longer latency and improved breastfeeding among participants, with more benefit seen among Black women. The adaptation of the CenteringPregnancy model to the antepartum service should be further explored.View Large Image Figure ViewerDownload Hi-res image Download (PPT)