Urticaria Due To Natto (Fermented Soybeans)
Clinical and Experimental Dermatology(2021)
Abstract
Natto is a traditional Japanese food of fermented soybeans, in which Bacillus subtilis produces natto-mucilage as metabolic product. Different from soy allergy, natto-mucilage has been reported as a cause of natto-induced late-onset anaphylaxis occurring 5-12 hours after ingestion. Anaphylaxis was the primary clinical manifestation reported in natto-induced hypersensitivity. Here, we report that natto can cause urticaria as a sole symptom without developing into anaphylaxis.
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