Study of controlled release of ibuprofen magnetic nanocomposites

•Controlled drug delivery (CDD) systems allow the kinetic and spatial control of the release.•These systems are often obtained using magnetic nanoparticles, biodegradable and biocompatible polymers.•Polylactic acid (PLA) is the matrix of the ibuprofen CDD system here presented.•Ibuprofen CDD system was prepared by melting mixing•The in vitro profile study of drug release showed to be sustained and prolonged.•The presence of magnetite is changing the porosity of the matrix, speeding up the drug release.