Clinical And Epidemiological Profile Of Atopic Dermatitis (Ad) In A Reference Center In An Emerging Country

Atopic Dermatitis (AD) is a chronic inflammatory skin disease with multifactorial etiology. This study evaluated the clinical and epidemiological profile of patients with Atopic Dermatitis in a reference center. Cross-sectional study performed by analyzing the medical records of AD patients from Jan/2018-19 in a reference center. Data were analyzed concerning sex, age, severity, treatment, concomitance with other atopic diseases, evaluation of eosinofilia and the management. We evaluated 240 patients (male = 58.75%) with mean age of 11 years. Regarding classification, 67.08% were mild, 18.33% moderate and 14.59% severe according to SCORAD (Scoring Atopic Dermatitis). Allergic rhinitis was observed in 91.66%, asthma in 55%, IgE-mediated food allergy in 11.25% and allergic conjunctivitis in 35.41%. Eosinophilia was observed in 39.16% of patients and was related to greater severity. Regular hydration was reported by 68.75% of patients. Ciclosporin was used by 12.08% of patients. Less than 2% are using monoclonal antibodies (MA) due to the difficulty of accessing these drugs. AD is a multifactorial chronic disease disease with difficult management and is associated with other atopies. Eosinophilia seems to be a marker of severity in this convenience sample and appears to be an inexpensive biomarker for everyday use in our clinical practice. Hydration is the main pillar of treatment, but it had partial adherence. Thereby, new strategies must be developed with these patients in order to improve adherence and quality of life through multidisciplinary teams. In more severe cases the use of immunosuppressants and MA was necessary.