Abstract MP109: SVEP1, a Novel Human Coronary Artery Disease Locus, Induces Vascular Smooth Muscle Cell Proliferation and Phenotypic Modulation Through Notch and Integrin Signaling

Jared Elenbaas,In-Hyuk Jung, Katherine Santana,Arturo Alisio,Nathan Stitziel

Arteriosclerosis, Thrombosis, and Vascular Biology（2020）

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Introduction and Hypothesis: A novel association between a variant in SVEP1 and coronary artery disease (CAD) was recently identified (OR=1.14, p=4.2x10-10). SVEP1 encodes an extracellular matrix (...

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