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Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease

Oliver Hartmann,Michaela Reissland,Carina R. Maier,Thomas Fischer,Cristian Prieto-Garcia,Apoorva Baluapuri,Jessica Schwarz,Werner Schmitz,Martin Garrido-Rodriguez,Nikolett Pahor,Clare C. Davies,Florian Bassermann,Amir Orian,Elmar Wolf,Almut Schulze,Marco A. Calzado,Mathias T. Rosenfeldt,Markus E. Diefenbacher

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY（2021）

Cited 25|Views48
Key words
non-small cell lung cancer,CRISPR-Cas9,mouse model,lung cancer,MYC,JUN,KRAS,TP53
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