[OA030] Improved dose sensitivity of N-(isobutoxymethyl) acrylamide polymer gel dosimeters for radiation therapy

Physica Medica(2018)

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摘要
Purpose A new and very low dose sensitivity of polymer gel dosimeter containing N-(isobutoxymethyl) acrylamide was introduced (Salah et al., 2017). A significant increase in dose response as well as dose sensitivity of N-(isobutoxymethyl) acrylamide polymer gel dosimeter has been reported in this study. Methods The N-(isobutoxymethyl) acrylamide (NIBMA) gels were fabricated under a fume hood in normal atmospheric conditions. Gels were irradiated by X-ray beams of a medical linear accelerator. The irradiated gel dosimeters were evaluated using nuclear magnetic imaging (NMR) techniques in terms of relaxation time (T2) of hydrogen protons within the water molecule. Results The dose response as well as dose sensitivity were significantly increased by increasing NIBMA concentration. Slight effects of dose rate, beam energy and post-irradiation stability were noticed on the performance of NIBMA polymer gel dosimeters. Conclusions High dose sensitivity with low toxicity polymer gel dosimeters containing N-(isobutoxymethyl) acrylamide (NIBMA) were developed for radiotherapy treatment planning system.
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