Group of cardia adenocarcinoma prognosis prediction markers and application thereof

The invention belongs to the technical field of biology, and relates to a cardia adenocarcinoma prognosis prediction technology, in particular to a group of cardia adenocarcinoma prognosis predictionmarkers and application thereof, namely the application of the detection reagent of specifically detecting ZBED5, CUL5, AVIL and USP15 or the group of gene expression products in the cardia adenocarcinoma prognosis prediction kit. A detection object of the kit is a cardia adenocarcinoma surgical excision tissue sample or an endoscopic biopsy tissue sample. The kit provided by the invention is usedfor prognosis prediction of cardia adenocarcinoma, so that prognosis prediction of cardia adenocarcinoma is more convenient and feasible; in addition, the prediction sensitivity of the combination ofthe four markers to the three-year life cycle of the cardia adenocarcinoma patient is 89.1%, and the specificity is 70.2%.