Polymorphism in the ZNF804A Gene and Variation in D1 and D2/D3 Dopamine Receptor Availability in the Healthy Human Brain: A Dual Positron Emission Tomography Study

Catherine E Hegarty,Angela M Ianni,Philip D Kohn,Bhaskar Kolachana,Michael Gregory,Joseph C Masdeu,Daniel P Eisenberg,Karen F Berman

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging（2023）

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摘要

These data suggest that ZNF804A genotype may be meaningfully linked to dopaminergic function in the human brain. The results also may provide information to guide future studies of ZNF804A-related mechanisms of schizophrenia risk.

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关键词

Dopamine,Genetics,Imaging,PET,Schizophrenia,ZNF804A

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