Negative pressure wound therapy with instillation and dwell time in the wound management of necrotizing fasciitis

•Necrotizing fasciitis is a life-threatening soft tissue infection and management of this condition remains challenging.•Negative pressure wound therapy with instillation and dwell time (NPWTi-d) has showed clinical advantages.•However, there is a paucity of literature regarding the role of NPWTi-d in management of necrotizing fasciitis.•We assessed the clinical outcomes of NPWTi-d in treating of necrotizing fasciitis in a relatively larger patients samples.•NPWTi-d facilitates wound cleansing and wound bed preparation and serves a new modality for managing necrotizing fasciitis.